PerkinElmer QSight® LC/MS/MS System

Built for sludge, grease, and the nastiest matrices you can throw its way. With unmatched robustness and minimal sample prep, the QSight® 500 LC/MS/MS System tr ...

In food safety testing, instrument reliability under real-world conditions is the true test of performance. This technical note showcases the durability and consistency of the PerkinElmer QSight^® 500 LC/MS/MS system through an intensive robustness study, analyzing high-matrix food samples with minimal cleanup and no loss in sensitivity.

Tomato is a moisture rich, pigment heavy matrix that makes multiresidue pesticide testing harder than it looks, and conventional QuEChERS cleanup adds real time and cost to every batch.

Part 1: Method Development and Verification with Quality Control Samples

In this first installment of a 4-part application note series, we detail a validated LC-MS/MS workflow for the analysis of 40 targeted PFAS compounds in water samples using PerkinElmer QSight^® 500 LC/MS/MS system and an automated solid-phase extraction (SPE) platform.

Per‑ and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants that can accumulate in animal‑derived foods, creating growing regulatory and public health concerns.

In France, TERA Environnement is breaking new ground in outdoor air analysis, using the PerkinElmer QSight^® LC/MS/MS system to measure PFAS contamination with unmatched sensitivity and minimal sample prep.

Growing health concerns regarding Per- and polyfluoroalkyl substances (PFAS) and their prevalence in consumer goods and the environment indicates a critical nee ...

In food safety and pesticide residue testing, accurate measurement of fosetyl-Al and its metabolite phosphonic acid is essential to ensure compliance with EU Maximum Residue Limits (MRLs) and to protect consumer health. T

This application note demonstrates a fast, sensitive, and highly robust LC‑MS/MS solution for honey authenticity testing through targeted quantification of 3‑methoxytyramine (3‑MT), a specific marker of beet‑sugar feeding.

The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.

Part 2: Application to Surface Water and Wastewater Samples

PFAS contamination in surface water and wastewater is a growing global concern, prompting the need for sensitive, efficient, and EPA-compliant analytical solutions. This is Part 2 of a 4-part application note series showcasing a robust LC-MS/MS workflow aligned with US EPA Method 1633, now applied to real-world water samples.

Part 3: Application to Sand, Soil, Sediment, Sludge, Biosolid and Other Solid Samples

From remediation sites to agricultural lands, testing PFAS in solid samples is no longer optional; it’s essential. Part 3 of this 4-part application note series details a comprehensive LC-MS/MS workflow for the analysis of 40 PFAS compounds in soil and sediment, fully aligned with US EPA Method 1633.

Part 4: Application to Fish and Other Animal Tissue Samples

Monitoring PFAS in biological samples like fish and animal tissue is essential for food safety and environmental risk assessment, but it presents unique challenges due to complex matrices and variable recoveries. Part 4 of this 4-part application note series demonstrates a validated sample prep and LC-MS/MS workflow tailored to meet these challenges while complying with US EPA Method 1633.

Designed to tackle the challenges faced by environmental testing labs analyzing PFAS and other emerging contaminants, the QSight^® 500 LC/MS/MS System provides a robust solution for handling complex matrices.

No matter what your application or matrices, our liquid chromatography and mass spectrometry (LC/MS) systems deliver the speed, sensitivity, exact mass information, wide dynamic range, and mass accuracy you need for having complete confidence in your results.

Demanding chromatography applications, from QA/QC to research, need to be supported by powerful software that addresses the need for ease-of-use and different proficiency levels.

PerkinElmer is committed to providing reliable consumables that support chromatographers across the globe. We supported the growth of chromatography into the wide-spread technique it has become, and we're still here serving separation scientists today.